- Modular barrel design with customized process length L/D to each individual product
- Modular screw design with broad selection of screw elements for high process flexibility
- Intensive mixing and dispersion of the twin screws for supreme product quality
- Specific torque up to 18 Nm/cm³ allowing low ratios of throughput/rpm resulting in minimized product temperatures and API degradation
- Manufactured in GMP design
- All parts coming in contact with the product made of stainless steel with minimized surface roughness
- Use of FDA-conformant oils/lubricants
- Complete documentation of all process parameters (V-lifecycle) based on URS (User requirement specification)
- Compact design and therefore low space requirement
- Self-cleaning of the twin screws avoids dead spaces and results in short residence times
- Clear arrangement of the extruder with easy operation, easy access for cleaning and maintenance
- Simple handling and quick dismantling using quick release couplings
- PLC and visualisation system conform to CFR Part 11
- FAT (factory acceptance test) and SAT (site acceptance test)
- Reliable scale-up due to geometrical constancy within the ZSK series
- Professional process engineering support with know-how from over 30 years of experience in pharmaceutical applications
- Comprehensive after-sales services by worldwide Coperion service network
Pharma Extruders
First-class twin screw extruders for continuous mixing of pharmaceutical active ingredients
Coperion is pioneer in the development of high-end closely intermeshing, co-rotating twin screw extruders. We possess a unique know-how and an extraordinary wealth of experience in this continuous production process. Since the beginning of pharmaceutical extrusion we have continuously set new standards in the continuous manufacturing of pharmaceutical products with our special ZSK pharma extruders. This begins with special applications on a laboratory scale and extends right through to continuous pharmaceutical production systems.
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